In this paper, a method of large-aperture (500 mm) and high sensitivity moire deflectometry is presented and used to obtain the multidirectional deflectograms of asymmetric flow field in high ultrasonic speed shock wave uind tunnel (M =10.29). At the same time, a 3-D reconstructive method of asymmetric flow field is presented which is based on the integration of moire deflective angle and double cubic many-Knot interpolating splines, and is used to calculate the 3-D density distribution of the asymmetric flow field.