For the vision measurement of aero large parts and components, traditional camera calibration methods relies on the high precision of standard targets which are difficult to be produced. The precision of these methods can not meet the need of large field of view for traditional camera calibration. Aiming at these problems, a site-calibration method based on collinear constraints of mark points located at the four corners is put forward. Some calibration control points are arranged close to the principal point within space measurement field of view, and the calibration initial results can be solved using the linear transformation. The collinear constraint rulers are placed in the field of four corners, the distortion coefficients can be calibrated using cross-ratio invariability and linear fitting. The number of control points and the whole parameters of calibration can be optimized, and the optimal site-calibration result can be obtained. The relative calibration experimental results show that in the field of view of 2.5 m×1.8 m, the reconstruction error of site is less than 0.07%, which meets the demand that the high precision of site-calibration, and has good robustness and adaptability for the vision measurement of aero large parts.