To reduce computational complexity of 3GPP long term evolution (LTE) uplink diversity reception in multiple antennas system, improve the hardware processing efficiency and achieve relatively good system performance, interference rejection combining (IRC), maximum ratio combining (MRC), simplified interference rejection combining (SIRC) and simplified maximum ratio combining (SMRC) algorithms were compared with simulation analysis of different interference strength in eight antennas system. According to the simulation results, when using SIRC algorithm in eight antennas system, computational complexity can be reduced to 1/(8N) with 1 dB SNR loss, and efficiency can be improved by the method of antennas subarray division. SIRC rather than IRC is used when there is strong correlated interference, SMRC rather than MRC is used when there is weak or negligible interference for diversity reception. As a result, the performance degrades somewhat while computational complexity can be reduced greatly.