The in-situ WB-CrB reinforced Ni-based composite coating is synthesized by laser cladding on steel 45# by prior to pasting. The microstructure and phase analyses are performed by X-ray diffractometer (XRD),optical microscope,scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). The microhardness and tribological properties of the coatings are also investigated. The results indicate that the coating epitaxial growing from the substrate with excellent bonding between the coating and substrate is ensured by the strong metallurgical interface. The microstructure at the bottom of the cladding layer mainly consists of orients dendrites of γ(NiFe). The microstructure at the middle and upper zones contains WB-CrB particles dispersed in the matrix of γ(NiFe). Compared with a pure Ni60 coating,the hardness of the WB-CrB complex particulate-reinforced composite coating is enhanced to HV0.31350. The wear and tear mass loss in a block on ring test against hardened steel is reduced by a factor of seven. This can be attributed to the presence of in-situ synthesized WB-CrB complex particles and their well distribution in the coating.