Due to the changes of environment and the axes of optoelectronic tracking system during the pointing calibration by stars along with the time, people cannot get a very precise result all the time. The problem is considered and the algorithm based on WLMS is introduced to meet the needs of two types. One is to get precise calibration result in a small area of the sky. And the other is to get the precise calibration in real time guiding. Two simulations are introduced to verify the feasibility and validity of the algorithm by using the data gotten from the field.