• High Power Laser Science and Engineering
  • Vol. 13, Issue 1, 01000e11 (2025)
Katarzyna Liliana Batani1,*, Marcia R. D. Rodrigues2, Aldo Bonasera2,3, Mattia Cipriani4..., Fabrizio Consoli4, Francesco Filippi4, Massimiliano M. Scisciò4, Lorenzo Giuffrida5, Vasiliki Kantarelou5, Stanislav Stancek5,6, Roberto Lera7, Jose Antonio Pérez-Hernández7, Luca Volpe7,8, I. C. Edmond Turcu9,10, Matteo Passoni11, Davide Vavassori11, David Dellasega11, Alessandro Maffini11, Marine Huault12,13, Howel Larreur12,13,14, Louis Sayo13, Thomas Carriere13, Philippe Nicolai13, Didier Raffestin13, Diluka Singappuli13 and Dimitri Batani13|Show fewer author(s)
Author Affiliations
  • 1Institute of Plasma Physics and Laser Microfusion (IPPLM), Warsaw, Poland
  • 2Cyclotron Institute, Texas A&M University, College Station, Texas, USA
  • 3Laboratori Nazionali del Sud-INFN, Catania, Italy
  • 4ENEA, Nuclear Department, C.R. Frascati, Frascati, Italy
  • 5ELI Beamlines Facility, The Extreme Light Infrastructure ERIC, Dolni Brezany, Czech Republic
  • 6Joint Laboratory of Optics of Palacky University and Institute of Physics of Academy of Sciences of the Czech Republic, Faculty of Science, Palacky University, Olomouc, Czech Republic
  • 7Centro de Láseres Pulsados (CLPU), Villamayor, Spain
  • 8ETSI Aeronaútica y del Espacio, Universidad Politécnica de Madrid, Madrid, Spain
  • 9UKRI/STFC Central Laser Facility, Rutherford Appleton Laboratory, Didcot, UK
  • 10Extreme Light Infrastructure: Nuclear Physics (ELI-NP), Magurele, Romania
  • 11Dipartimento di Energia, Politecnico di Milano, Milano, Italy
  • 12Departamento de Física fundamental, Facultad de Ciencias, Universidad de Salamanca, Salamanca, Spain
  • 13CELIA – Centre Lasers Intenses et Applications, Université de Bordeaux, Talence, France
  • 14HB11 Energy, Sydney, Australia
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    DOI: 10.1017/hpl.2024.92 Cite this Article Set citation alerts
    Katarzyna Liliana Batani, Marcia R. D. Rodrigues, Aldo Bonasera, Mattia Cipriani, Fabrizio Consoli, Francesco Filippi, Massimiliano M. Scisciò, Lorenzo Giuffrida, Vasiliki Kantarelou, Stanislav Stancek, Roberto Lera, Jose Antonio Pérez-Hernández, Luca Volpe, I. C. Edmond Turcu, Matteo Passoni, Davide Vavassori, David Dellasega, Alessandro Maffini, Marine Huault, Howel Larreur, Louis Sayo, Thomas Carriere, Philippe Nicolai, Didier Raffestin, Diluka Singappuli, Dimitri Batani, "Generation of radioisotopes for medical applications using high-repetition, high-intensity lasers," High Power Laser Sci. Eng. 13, 01000e11 (2025) Copy Citation Text show less

    Abstract

    We used the PW high-repetition laser facility VEGA-3 at Centro de Láseres Pulsados in Salamanca, with the goal of studying the generation of radioisotopes using laser-driven proton beams. Various types of targets have been irradiated, including in particular several targets containing boron to generate α-particles through the hydrogen–boron fusion reaction. We have successfully identified γ-ray lines from several radioisotopes created by irradiation using laser-generated α-particles or protons including 43Sc, 44Sc, 48Sc, 7Be, 11C and 18F. We show that radioisotope generation can be used as a diagnostic tool to evaluate α-particle generation in laser-driven proton–boron fusion experiments. We also show the production of 11C radioisotopes, $\approx 6 \times 10^{6}$ , and of 44Sc radioisotopes, $\approx 5 \times 10^{4}$ per laser shot. This result can open the way to develop laser-driven radiation sources of radioisotopes for medical applications.
    p+11B3(4He)+8.7MeV, ((1))

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    D=γ line activityNumber of counts. ((3))

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    1hν1hν=1mc2(1cosθ). ((4))

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    11C11B+e++νe, ((5))

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    p+11B11C+n2.765MeV. ((6))

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    18F18O+e++νe, ((7))

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    α+14N18F+γ+4.415MeV ((8))

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    18O+p18F+n2.44MeV ((9))

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    D=Activity[kBq]Counts0.0001, ((10))

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    A=Nλ,λ=0.693T1/2, ((11))

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    N31#=6.0×106. ((12))

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    (α11C)exp=(3×1062×106)exp1.5,(α11C)cal=(0.84×1060.97×106)cal0.9. ((13))

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    A[kBq]=D×Counts0.065kBq, ((14))

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    N31#=654.76×1051.4×106. ((15))

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    10μANα [s1]=105C/s2×1.6×1019 C=3×1013s1. ((16))

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    f=3×1013per second1012 per shot=30Hz. ((17))

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    Katarzyna Liliana Batani, Marcia R. D. Rodrigues, Aldo Bonasera, Mattia Cipriani, Fabrizio Consoli, Francesco Filippi, Massimiliano M. Scisciò, Lorenzo Giuffrida, Vasiliki Kantarelou, Stanislav Stancek, Roberto Lera, Jose Antonio Pérez-Hernández, Luca Volpe, I. C. Edmond Turcu, Matteo Passoni, Davide Vavassori, David Dellasega, Alessandro Maffini, Marine Huault, Howel Larreur, Louis Sayo, Thomas Carriere, Philippe Nicolai, Didier Raffestin, Diluka Singappuli, Dimitri Batani, "Generation of radioisotopes for medical applications using high-repetition, high-intensity lasers," High Power Laser Sci. Eng. 13, 01000e11 (2025)
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