Lu ZHANG, Liang XU, Zong-cai TU, Qi-ming ZHOU, Wen-na ZHOU. Mechanism of Isoquercitrin Inhibiting Advanced Glycation Products Formation Based on Fluorescence Spectroscopy Technique[J]. Spectroscopy and Spectral Analysis, 2020, 40(12): 3755
- Spectroscopy and Spectral Analysis
- Vol. 40, Issue 12, 3755 (2020)
Fig. 1. Inhibitory activity of isoquercetin on the formation of AGEs on α-La-fructose system
Fig. 2. Influence of isoquercetin on the intrinsic fluorescence spectra of glycated α-La
Fig. 3. Synchronous fluorescence spectra of α-La with different concentrations of isoquercetin with Δλ fixed at 15 nm (a) and 60 nm (b), respectively
Fig. 4. Three-dimensional fluorescence spectra of α-La without (a) and with (b) isoquercetin
Fig. 5. (a) Influence of isoquercetin on the fluorescence emission spectra of α-La; (b) The Stern-Volmer plots of F 0/F versus isoquercetin concentrations [Q ]; (c) The double logarithmic plots of log[(F 0-F )/F ] versus log[Q ]; (d) The linear plot of lnKa versus 1/T
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Table 1. The fluorescence quenching constants, binding sites, binding constant and thermodynamic parameters for the interaction of isoquercetin with α-La
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