• Journal of Innovative Optical Health Sciences
  • Vol. 3, Issue 2, 123 (2010)
ZHEN WANG*, WEIHUA LUO, XIAOLI SUN, PENGCHENG LI, SHANGBIN CHEN, and QINGMING LUO
Author Affiliations
  • Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074, P. R. China
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    DOI: 10.1142/s1793545810000939 Cite this Article
    ZHEN WANG, WEIHUA LUO, XIAOLI SUN, PENGCHENG LI, SHANGBIN CHEN, QINGMING LUO. EFFECTS OF NAAG AND MPEP ON RAT CORTICAL SPREADING DEPRESSION[J]. Journal of Innovative Optical Health Sciences, 2010, 3(2): 123 Copy Citation Text show less
    References

    [1] J. M. Smith, D. P. Bradley, M. F. James, C. L. Huang, “Physiological studies of cortical spreading depression,” Biol. Rev. Camb. Philos. Soc. 81, 457– 481 (2006).

    [2] G. G. Somjen, “Mechanisms of spreading depression and hypoxic spreading depression-like depolarization,” Physiol. Rev. 81, 1065–1096 (2001).

    [3] J. Zhou, J. H. Neale, M. G. Pomper, A. P. Kozikowski, “NAAG peptidase inhibitors and their potential for diagnosis and therapy,” Nat. Rev. Drug Discov. 4, 1015–1026 (2005).

    [4] M. Lauritzen, A. J. Hansen, “The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression,” J. Cereb. Blood Flow Metab. 12, 223–229 (1992).

    [5] M. Lauritzen, “Pathophysiology of the migraine aura. The spreading depression theory,” Brain 117(Pt 1), 199–210 (1994).

    [6] C. Ayata, M. A. Moskowitz, “Cortical spreading depression confounds concentration-dependent pial arteriolar dilation during N-methyl-d-aspartate superfusion,” Am. J. Physiol. Heart Circ. Physiol. 290, 1837–1841 (2006).

    [7] R. Marrannes, R. Willems, E. De Prins, A. Wauquier, “Evidence for a role of the N-methyld- aspartate (NMDA) receptor in cortical spreading depression in the rat,” Brain Res. 457, 226–240 (1988).

    [8] H. Kruger, U. Heinemann, H. J. Luhmann, “Effects of ionotropic glutamate receptor blockade and 5- HT1A receptor activation on spreading depression in rat neocortical slices,” Neuroreport 10, 2651–2656 (1999).

    [9] B. Nellgard, T. Wieloch, “NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain,” Acta Physiol. Scand. 146, 497–503 (1992).

    [10] D. D. Mitsikostas, M. S. del Rio, C. Waeber, Z. Huang, F. M. Cutrer, M. A. Moskowitz, “Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalis,” Br. J. Pharmacol. 127, 623–630 (1999).

    [11] Z. X. Xi, M. Kiyatkin, X. Li, X. Q. Peng, A. Wiggins, K. Spiller, J. Li, E. L. Gardner, “N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaineenhanced brain-stimulation reward in rats,” Neuropharmacology 58, 304–313 (2010).

    [12] T. Yamamoto, A. Kozikowski, J. Zhou, J. H. Neale, “Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain,” Mol. Pain 4, 31 (2008).

    [13] Z. Cai, S. Lin, P. G. Rhodes, “Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia,” Eur. J. Pharmacol. 437, 139–145 (2002).

    [14] S. Ghose, K. A. Gleason, B. W. Potts, K. Lewis- Amezcua, C. A. Tamminga, “Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: A mechanism for antipsychotic drug action ” Am. J. Psychiatry 166, 812–820 (2009).

    [15] V. Bruno, I. Ksiazek, G. Battaglia, S. Lukic, T. Leonhardt, D. Sauer, F. Gasparini, R. Kuhn, F. Nicoletti, P. J. Flor, “Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective,” Neuropharmacology 39, 2223–2230 (2000).

    [16] A. Gorji, “Spreading depression: A review of the clinical relevance,” Brain Res. Rev. 38, 33–60 (2001).

    [17] A. M. Ba, M. Guiou, N. Pouratian, A. Muthialu, D. E. Rex, A. F. Cannestra, J. W. Chen, A. W. Toga, “Multiwavelength optical intrinsic signal imaging of cortical spreading depression,” J. Neurophysiol. 88, 2726–2735 (2002).

    [18] A. Van Hemelrijck, S. Hachimi-Idrissi, S. Sarre, G. Ebinger, Y. Michotte, “Neuroprotective effect of Nacetyl- aspartyl-glutamate in combination with mild hypothermia in the endothelin-1 rat model of focal cerebral ischemia,” J. Neurochem. 95, 1287–1297 (2005).

    [19] C. Bellone, C. Luscher, M. Mameli, “Mechanisms of synaptic depression triggered by metabotropic glutamate receptors,” Cell Mol. Life Sci. 65, 2913–2923 (2008).

    [20] S. Chen, P. Li, W. Luo, H. Gong, S. Zeng, Q. Luo, “Origin sites of spontaneous cortical spreading depression migrated during focal cerebral ischemia in rats,” Neurosci. Lett. 403, 266–270 (2006).

    [21] Z. Wang, P. Li, W. Luo, S. Chen, Q. Luo, “Periinfarct temporal changes in intrinsic optical signal during spreading depression in focal ischemic rat cortex,” Neurosci. Lett. 424, 133–138 (2007).

    [22] T. A. Basarsky, S. N. Duffy, R. D. Andrew, B. A. MacVicar, “Imaging spreading depression and associated intracellular calcium waves in brain slices,” J. Neurosci. 18, 7189–7199 (1998).

    [23] M. Guiou, S. Sheth, M. Nemoto, M. Walker, N. Pouratian, A. Ba, A. W. Toga, “Cortical spreading depression produces long-term disruption of activity-related changes in cerebral blood volume and neurovascular coupling,” J. Biomed. Opt. 10, 11004 (2005).

    [24] J. H. Neale, R. T. Olszewski, L. M. Gehl, B. Wroblewska, T. Bzdega, “The neurotransmitter Nacetylaspartylglutamate in models of pain, ALS, diabetic neuropathy, CNS injury and schizophrenia,” Trends Pharmacol. Sci. 26, 477–484 (2005).

    [25] F. Richter, A. Lehmenkuhler, “[Cortical spreading depression (CSD): A neurophysiological correlate of migraine aura],” Schmerz 22, 544–546, 548–550 (2008).

    [26] D. Pietrobon, “Familial hemiplegic migraine,” Neurotherapeutics 4, 274–284 (2007).

    [27] C. Ayata, M. Shimizu-Sasamata, E. H. Lo, J. L. Noebels, M. A. Moskowitz, “Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the alpha1A subunit of P/Q type calcium channels,” Neuroscience 95, 639–645 (2000).

    [28] T. Horiguchi, B. Kis, N. Rajapakse, K. Shimizu, D. W. Busija, “Cortical spreading depression (CSD)-induced tolerance to transient focal cerebral ischemia in halothane anesthetized rats is affected by anesthetic level but not ATP-sensitive potassium channels,” Brain Res. 1062, 127–133 (2005).

    [29] N. Cholet, L. Pellerin, P. J. Magistretti, E. Hamel, “Similar perisynaptic glial localization for the Na+, K+-ATPase alpha 2 subunit and the glutamate transporters GLAST and GLT-1 in the rat somatosensory cortex,” Cereb. Cortex 12, 515–525 (2002).

    [30] A. Simonyi, T. R. Schachtman, G. R. Christoffersen, “The role of metabotropic glutamate receptor 5 in learning and memory processes,” Drug News Perspect. 18, 353–361 (2005).

    [31] P. M. Lea, A. I. Faden, “Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP,” CNS Drug Rev. 12, 149–166 (2006).

    [32] P. Malherbe, N. Kratochwil, M. T. Zenner, J. Piussi, C. Diener, C. Kratzeisen, C. Fischer, R. H. P. Porter, “Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl- 6-(phenylethynyl)-pyridine,” Mol. Pharmacol. 64, 823 (2003).

    [33] W. P. Spooren, F. Gasparini, T. E. Salt, R. Kuhn, “Novel allosteric antagonists shed light on mglu (5) receptors and CNS disorders,” Trends Pharmacol. Sci. 22, 331–337 (2001).

    ZHEN WANG, WEIHUA LUO, XIAOLI SUN, PENGCHENG LI, SHANGBIN CHEN, QINGMING LUO. EFFECTS OF NAAG AND MPEP ON RAT CORTICAL SPREADING DEPRESSION[J]. Journal of Innovative Optical Health Sciences, 2010, 3(2): 123
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