Both of the fluorescence and polarization spectral characteritic of steady-state and polarized fluorescence induced by 407 nm laser of normal and the alcoholic whole blood are studied. By calculating the polarization degree and the rotation-relaxation time of the two blood cells,the depolarization effect of alcoholism blood is less than the normal one,but the rotation-relaxation time is opposite. The result is in accordance with the hemorheologic measurements. Because of alcoholism,viscidity of blood and the volume of erythrocyte become greater. The combined action of the two changes induces the regularity variation of fluorescence intensity,polarization degree and the rotation-relaxation time of the normal and alcoholism blood cells.