The mixed powders of Co-based alloy (stellite-6) and vanadium carbide (VC) are deposited on SUS304 stainless steel using fiber laser and coaxial laser cladding head. The two methods with a constant chemical composition multi-layer cladding and a functionally gradient material multi-layer cladding are investigated comparatively. The results show that the microstructures of the clad layer with the mixed powder of stellite-6 and VC can be classified into hypoeutectic structure and hypereutectic structure according to the concentration of VC; the functionally gradient material multi-layer cladding is an effective method to decrease the crack sensitivity.