Author Affiliations
1School of Microelectronics, Southern University of Science and Technology, Shenzhen 518055, China2School of Fashion & Textiles, The Hong Kong Polytechnic University, Hong Kong SAR, China3Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China4Research Institute for Intelligent Wearable Systems (RI-Wear), The Hong Kong Polytechnic University, Hong Kong SAR, Chinashow less
Fig. 1. (Color online) Textile-based sweat biosensors show promising applications in non-invasive and wearable health monitoring. Research advances in understanding the biosensing mechanism, efficient sweat collection strategies, high-performance biosensor fabrication, and system integration are critical to achieving desired textile-based sensing platforms.
Fig. 2. (Color online) Schematic diagram of electrochemical biosensor system. A typical electrochemical biosensor includes identification module, sensor module, signal processing, transmission module, and power supply module.
Fig. 3. (Color online) Response mechanisms of ion-selective membrane. (a) The capacitive redox mechanism (with PEDOT as an example). (b) The capacitance mechanism of EDL (with carbon as an example).
Fig. 4. (Color online) Example for 1D fiber-based sensor and 2D cloth-based sensor. (a) The morphology and mechanism of lactate working electrode. (b) Schematic diagram and physical diagram of the lactic acid sensor,
Fig. 5. (Color online) Sampling in wearable sweat sensors. (a) Sweat rate of various parts of the human body under different exercise intensities
[70]. (b) Efficient sweat collection strategy on textiles with fast water absorption properties and laser-engraved dendritic bifurcated channels
[67]. (c) A superhydrophilic/superhydrophobic Janus structure on textiles for directional sweat transport
[69]. (d) Sweat collection system using absorbent material for storage and hydrophilic cotton thread to transport sweat
[68].
Fig. 6. (Color online) Examples of nano-structure functional material for Improvement. (a) Improving the detection limit of sweat sensors for biomarkers by incorporating dendritic gold nanostructures on electrodes
[76]. (b) Using semiconductor ZnO nanowires to improve the sensitivity of test equipment
[77]. (c) Strategies for controlling standard potentials without the need for external instruments
[78].
Fig. 7. (Color online) Two common types of physically bonded connections. (a) Electronic components are connected to wires by soldering and then integrated with other modules on the garment. (b) The snap fasteners, wires, components, and cloth are connected using a compilation.
Fig. 8. (Color online) Textile-based sensor system integration approaches. (a) Using near-field clothing systems to establish wireless power and data connections around the human body
[97]. (b) Textile-based micro networks rely on human activities to work together and modulate harvested energy via supercapacitors for high power output
[98]. (c) Textile system embroidered with liquid metal
[99]. (d) Textile-based embroidery antenna
[100].
Classification | Substrate | Fabrication method | Conductivity | Sensitivity | Biomarker | Long-term stability | Reference |
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Fiber | Carbon fibers | Integrated TiO2 nanotubes into the conductive carbon yarns (CCY) | High electrical conductivity: CCY has high electrical conductivity. | Desirable sensitivity, wide-range response (10 fg to 1µg/mL), and good limit of detection (6 fg/mL) | Cortisol | Initial current response remained at 94.70 % after 4 weeks | [49] | Gold fiber | Prussian blue and glucose oxidase | High electrical conductivity: The average conductivity of the stretchable Au fibers glucose is about 93 S/cm, it has chemical inertness and high conductivity. | A linear range of 0–500µM and a sensitivity of 11.7µA/(mM·cm2) | Glucose | Stable chronoamperometricresponses in 6 h operation and 8 days of storage | [50] | Gold fiber | Dry spinning | High electrical conductivity: superior performance in conductivity | 19.13µA/(mM·cm2) in PBS and 14.6µA/(mM·cm2) in artificial sweat | Lactate | 88% current retention after 100 stretching cycles; 71% redox current retention after a 6-day storage | [44] | Cloth | Carbon textile | Digital laser writing | High electrical conductivity: CCY has high electrical conductivity. | Desirable sensitivity, wide-range response (10 fg to 1µg/mL), and good limit of detection (6 fg/mL), along with accuracy. | Glucose, lactate acid, AA, UA, Na+, and K+ | Negligible changes over 4 weeks (<6.4 %) | [51] | Cloth | Screen-printing and coating | High electrical conductivity: the MWCNTs were an excellent conductive material and could facilitate the electron transfer rate | Acceptable detection range (0.05−1 mM) and sensitivity (105.93µA/(mM·cm2)) | Glucose | Good long-term stability | [52] | Graphene-based nanocomposite | Counter electrodes (CE) filled with modified G-PU-RGO-PB paste | High electrical conductivity: functionalize graphene oxide (GO) using TEPA by solution mixing method to enhance electrical conductivity | The RSD is 3.06%. It can potentially be utilized in detecting lactate from sweat with LOD of 0.4 mM and LOQ of 1.3 mM reliably. | Lactate | The change in anodicand the cathodic current was very negligible after washing. | [46] |
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Table 1. Examples based on two types of textile substrates.