Author Affiliations
State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering,Zhejiang University, Hangzhou, Zhejiang 310027, Chinashow less
Fig. 1. Diagram of TD-OCM system and axial PSF
[23]. (a) Schematic of TD-OCM system; (b) comparison of axial PSF under confocal and coherence-gated configuration of OCM system
Fig. 2. Schematic of FD-OCM system and comparison of sensitivity between TD-OCM and FD-OCM. (a) Schematic of FD-OCM system; (b) comparison of sensitivity between TD-OCM and FD-OCM with Gaussian source at 1300 nm
[27] Fig. 3. Overview of FF-OCM system
Fig. 4. Principle of data acquisition in FF-OCM system
Fig. 5. Illustrations of scanning imaging modes of PS-OCM and FF-OCM. (a) Scanning imaging mode of PS-OCM; (b) scanning imaging mode of FF-OCM
Fig. 6. Simulation of resolution varying with source central wavelength, bandwidth, and numerical aperture of objective in OCM. (a) Relation among axial resolution, source central wavelength, and bandwidth; (b) relation among lateral resolution, source central wavelength, and numerical aperture
Fig. 7. Ultrahigh resolution images of industrial sandpaper
[38]. (a) Industrial sandpaper with particle size about 125 μm; (b) sandpaper longitudinal section image of general system; (c) sandpaper cross section image of ultra-high resolution system
Fig. 8. High-resolution images of onion epithelium obtained by FF-OCM system
[29] Fig. 9. Images of scattering samples without and with random phase
[49].(a) Without random phase; (b) with random phase
Fig. 10. Axial resolution of OCM system versus detection depth and source bandwidth
[13]. (a) Axial resolution versus FWHM of the Gaussian spectrum at different depths of human epidermis; (b) reachable minimum axial resolution versus depth of epidermis
Fig. 11. Diagram of dark-field OCM with extended depth of focus in sample arm
Fig. 12. En face images of murine pancreas at different depths obtained by extended-focus OCM system
[68]. Scale bar: 200 μm. (a) 11 μm; (b) 54 μm; (c) 97 μm; (d) 110 μm
Fig. 13. Example of imaging process of human fingertip by GD-OCM
[71] Fig. 14. Cross-section images of African frog tadpole
[70]. (a) Image acquired by GD-OCM system; (b) image acquired by OCM system at fixed focal plane
Fig. 15. Images of posterior layers of human corneas of healthy and FED corneas
[91]. (a)(c)(d) Images of healthy cornea in the posterior elastic layer, endothelial cell layer, and posterior stromal layer; (b)(e)(f) images of FED cornea in the posterior elastic layer, endothelial cell layer, and posterior stromal layer
Fig. 16. Ex vivo images of cortical and subcortical structures in mouse brain slice
[39]. (a) Transmission image showing imaging area; (b) result of Vis-OCM imaging; (c)(d) Vis-OCM images, fluorescence images of labeled amyloid plaques, and overlays of cortical and subcortical structures
Fig. 17. En face images of fibroblast obtained by dynamic detection
[110]. Scale bar: 50 μm.(a)
En face image; (b) fiber stretch detection; (c) cell migration detection
Fig. 18. Diagram of focus-extended OCM and angiograms of mouse cortex
[109]. (a) Illustration of focus-extended system; (b)(c) interpolation process for angiogram; (d) angiogram of mouse cortex; (e)(f) quantitative distributions of total flow rate and axial flow rate
Category | CSLM | OCT | PS-OCM | FF-OCM |
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Axial resolution δz /μm | 0.5--2 | 0.5--8 | 0.5--8 | 0.5--8 | Lateral resolution δx /μm | 0.2--1 | 10--20 | 0.5--2 | 0.5--2 | Imaging depth zm /mm | <0.2 | 1--3 | <0.2 | — | Field of view xm /mm2 | 200--400 | >1000 | 200--400 | 200--400 | Imaging speed /(pixel·s-1) | <5×107 | >1×1010 | >1×1010 | (2--5)×109 | Power P /μW | ~1 | 10--100 | 10--100 | 0.5--2 | Sensitivity RSN /dB | <40 | 100--110 | 100--110 | 80--90 |
|
Table 1. Typical performance parameters of different imaging systems
[88-90]