The present paper primarily studied the feasibility of the measurement of composition concentration in turbid media using response variable transform (RVT) method. With intralipid as the subject, the simulation of Monte Carlo in conjunction with the IAD algorithm and the experiment of double-integrating-sphere system combined with the IAD algorithm were conducted to verify the effectiveness to extract the scattering information. Furthermore, for the feasibility of the scattering coefficient to predict the concentration of intralipid, the results showed that measuring the component concentration in turbid media by means of RVT method is effective and feasible, and the relative error to predict the concentration with the linear relationship between scattering coefficient and concentration of intralipid is less than 10%.