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Journals >
Chinese Optics Letters >
Volume 18 >
Issue 12 >
Page 121705 > Article
Chinese Optics Letters
Vol. 18, Issue 12, 121705 (2020)
Deep learning virtual colorful lens-free on-chip microscopy
Hua Shen
1、2、3、*
and Jinming Gao
1、2
Author Affiliations
1
School of Electronic Engineering and Optoelectronic Technology, Nanjing University of Science and Technology, Nanjing 210094, China
2
MIIT Key Laboratory of Advanced Solid Laser, Nanjing University of Science and Technology, Nanjing 210094, China
3
Department of Material Science and Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA
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DOI:
10.3788/COL202018.121705
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Hua Shen, Jinming Gao. Deep learning virtual colorful lens-free on-chip microscopy[J]. Chinese Optics Letters, 2020, 18(12): 121705
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Fig. 1.
Lens-free on-chip microscope setup. (a) Schematic of lens-free on-chip microscopy. (b) Experimental lens-free on-chip microscope setup. (c) An example image of H&E stained pathological tumor tissue.
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Fig. 2.
Computational algorithm flowchart to get a virtually colorized lens-free on-chip microscopy image.
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Fig. 3.
Deep learning GAN established to achieve virtual colorization.
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Fig. 4.
Data processing to achieve virtual colorful lens-free on-chip microscopy. The yellow scale bar is 200 μm.
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Fig. 5.
Comparisons of lens-free on-chip microscopy image, bench-top commercial microscopy image, and virtual colorization image, which are image pairs of ROIs #1, #2, and #3 in Fig.
4
.
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Hua Shen, Jinming Gao. Deep learning virtual colorful lens-free on-chip microscopy[J]. Chinese Optics Letters, 2020, 18(12): 121705
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Paper Information
Category: Biophotonics
Received: Aug. 22, 2020
Accepted: Oct. 29, 2020
Posted: Oct. 29, 2020
Published Online: Dec. 10, 2020
The Author Email: Hua Shen (edward_bayun@163.com)
DOI:
10.3788/COL202018.121705
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