• Chinese Optics Letters
  • Vol. 18, Issue 12, 121705 (2020)
Hua Shen1、2、3、* and Jinming Gao1、2
Author Affiliations
  • 1School of Electronic Engineering and Optoelectronic Technology, Nanjing University of Science and Technology, Nanjing 210094, China
  • 2MIIT Key Laboratory of Advanced Solid Laser, Nanjing University of Science and Technology, Nanjing 210094, China
  • 3Department of Material Science and Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA
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    DOI: 10.3788/COL202018.121705 Cite this Article Set citation alerts
    Hua Shen, Jinming Gao. Deep learning virtual colorful lens-free on-chip microscopy[J]. Chinese Optics Letters, 2020, 18(12): 121705 Copy Citation Text show less
    Lens-free on-chip microscope setup. (a) Schematic of lens-free on-chip microscopy. (b) Experimental lens-free on-chip microscope setup. (c) An example image of H&E stained pathological tumor tissue.
    Fig. 1. Lens-free on-chip microscope setup. (a) Schematic of lens-free on-chip microscopy. (b) Experimental lens-free on-chip microscope setup. (c) An example image of H&E stained pathological tumor tissue.
    Computational algorithm flowchart to get a virtually colorized lens-free on-chip microscopy image.
    Fig. 2. Computational algorithm flowchart to get a virtually colorized lens-free on-chip microscopy image.
    Deep learning GAN established to achieve virtual colorization.
    Fig. 3. Deep learning GAN established to achieve virtual colorization.
    Data processing to achieve virtual colorful lens-free on-chip microscopy. The yellow scale bar is 200 μm.
    Fig. 4. Data processing to achieve virtual colorful lens-free on-chip microscopy. The yellow scale bar is 200 μm.
    Comparisons of lens-free on-chip microscopy image, bench-top commercial microscopy image, and virtual colorization image, which are image pairs of ROIs #1, #2, and #3 in Fig. 4.
    Fig. 5. Comparisons of lens-free on-chip microscopy image, bench-top commercial microscopy image, and virtual colorization image, which are image pairs of ROIs #1, #2, and #3 in Fig. 4.
    Hua Shen, Jinming Gao. Deep learning virtual colorful lens-free on-chip microscopy[J]. Chinese Optics Letters, 2020, 18(12): 121705
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