Yulin ZENG, Jiajie CHEN, Zhengfang TIAN, Min ZHU, Yufang ZHU. Preparation of Mesoporous Organosilica-based Nanosystem for in vitro Synergistic Chemo- and Photothermal Therapy [J]. Journal of Inorganic Materials, 2020, 35(12): 1365
- Journal of Inorganic Materials
- Vol. 35, Issue 12, 1365 (2020)
1. Characterization of MONs
2. (a) Zeta potential, (b) FT-IR spectra and (c) UV-Vis spectra of MONs, MONs-NH2, ICG/DOX-MONs and ICG/DOX-MONs@DNA20 nanoparticles
3. Photothermal heating curves of ICG/DOX- MONs@DNA20 suspension with different concentrations under NIR irradiation at 0.75 W/cm2, and (b) photothermal heating curves of 100 μg/mL ICG/DOX-MONs@DNA20 suspension under NIR irradiation at different power densities
4. Release profiles of (a) DOX and (b) ICG from ICG/DOX-MONs@DNA20 at 37 and 43 ℃, respectively, and (c) release profile of DOX and ICG from ICG/DOX-MONs@DNA20 at the alternating temperature between 37 and 43 ℃
5. Cell viability of HeLa cells cultured with MONs with different concentrations for 24 and 48 h
6. Cell uptake of different nanoparticles after being cultured with HeLa cells for 3 h (blue: nuclei; red: DOX)
7. Cell viabilities of HeLa cells cultured with ICG/DOX-MONs and ICG/DOX-MONs@DNA20 with or without NIR irradiation
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