• Acta Optica Sinica
  • Vol. 40, Issue 22, 2210002 (2020)
Siqi Zhu1、2, Jue Wang1、2、*, and Yufang Cai1、2
Author Affiliations
  • 1Key Laboratory of Optoelectronic Technology and Systems of the Ministry of Education, Chongqing University, Chongqing 400044, China
  • 2Engineering Research Center of Industrial Computed Tomography Nondestructive Testing of the Ministry of Education, Chongqing University, Chongqing 400044, China
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    DOI: 10.3788/AOS202040.2210002 Cite this Article Set citation alerts
    Siqi Zhu, Jue Wang, Yufang Cai. Low-Dose CT Denoising Algorithm Based on Improved Cycle GAN[J]. Acta Optica Sinica, 2020, 40(22): 2210002 Copy Citation Text show less
    Cycle generative adversarial network model
    Fig. 1. Cycle generative adversarial network model
    Feature converter residual structure network model. (a) ResNet network model; (b) DenseNet network model
    Fig. 2. Feature converter residual structure network model. (a) ResNet network model; (b) DenseNet network model
    Generator network training model based on DenseNet
    Fig. 3. Generator network training model based on DenseNet
    5-layer DenseNet network model
    Fig. 4. 5-layer DenseNet network model
    Discriminator network training model
    Fig. 5. Discriminator network training model
    Algorithm flowchart
    Fig. 6. Algorithm flowchart
    Validation scheme of proposed method
    Fig. 7. Validation scheme of proposed method
    Denoising results of an image for patient No.48. (a) LDCT; (b) SDCT; (c) ST-NLM processed LDCT; (d) Res-CycleGAN processed LDCT; (e) Dense-CycleGAN processed LDCT
    Fig. 8. Denoising results of an image for patient No.48. (a) LDCT; (b) SDCT; (c) ST-NLM processed LDCT; (d) Res-CycleGAN processed LDCT; (e) Dense-CycleGAN processed LDCT
    Automatic calcification score of a computed tomography image. (a) SDCT Agatston score; (b) ST-NLM Agatston score; (c) Res-CycleGAN Agatston score; (d) Dense-CycleGAN Agatston score
    Fig. 9. Automatic calcification score of a computed tomography image. (a) SDCT Agatston score; (b) ST-NLM Agatston score; (c) Res-CycleGAN Agatston score; (d) Dense-CycleGAN Agatston score
    Denoising results of an image for patient No.79. (a) LDCT after adding noise; (b) original image; (c) ST-NLM; (d) Res-CycleGAN; (e) Dense-CycleGAN
    Fig. 10. Denoising results of an image for patient No.79. (a) LDCT after adding noise; (b) original image; (c) ST-NLM; (d) Res-CycleGAN; (e) Dense-CycleGAN
    ParameterKernel sizeBatch sizeDropoutLearning rateEpochλ
    Value3×3100.50.00021320.45
    Table 1. Model parameter
    MethodSNR /dBPSNR /dBSSIM
    LDCT8.986029.08310.6540
    ST-NLM10.688630.89660.7031
    Res-CycleGAN13.487633.79350.7962
    Dense-CycleGAN15.798338.55630.8391
    Table 2. Comparison of image performance indicators
    Siqi Zhu, Jue Wang, Yufang Cai. Low-Dose CT Denoising Algorithm Based on Improved Cycle GAN[J]. Acta Optica Sinica, 2020, 40(22): 2210002
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