Glass lasers can output the most powerful laser at present for laser fusion and laser-plasma interaction research. The great attention was paied to the Nd: doped fluorophosphate glass because of its low nonlinear refractive index n2 and suitable stimulated emission cross-section. Based on the composition effect of spectral properties and other physical properties of glass the practical glass composition and technology of fluorophosphate glass were determined. The results indicated that the glass has good physical properties and laser performances. The only problem remained is solid inclusions which are being attacked.