A theoretical method for calculating the loss spectrum of the hollow fiber inner-coated with multi-dielectric-layer and silver layer was proposed. The transmission loss characteristics of infrared hollow fibers were analyzed theoretically. The film thickness for each dielectric layer was estimated according to the measured loss spectra by introducing the film thickness, material dispersion, and surface roughness into the theoretical calculation. The fabrication parameters of liquid-phase coating and iodization process for SiO2 and AgI film were adjusted by comparing the measured and the calculated loss spectra. A hollow fiber with Ag/SiO2/AgI/SiO2 structure was fabricated and low-loss property was demonstrated in the mid-infrared wavelength region.