A design scheme of adaptive neural controller is proposed for a class of uncertain MIMO nonlinear time-varying delay system with unknown nonlinear dead-zones and known function control gain. The design is based on the principle of sliding mode control. The unknown time-varying delay uncertainties are compensated by using appropriate Lyapunov-Krasovskii Functionals in the design. By utilizing the integral Lyapunov Function and constructing approximated continuous functions, the closed-loop control systems is proved to be semi-globally uniformly ultimately bounded. Simulation results demonstrate the effectiveness of the approach.