This research analyzes the spatial distribution pattern of industrial point sources and pollution loads in Zhangjiakou city, a central city in the northwest of Heibei province by buffer analysis and hotspot analysis, based on sewage industrial point source information database. The results show that: (1) Industrial point sources are concentrated in neighboring districts on the southeast-west axis of the main urban area. The industrial point source pollution of Zhangbei county and Xuanhua district are the heaviest. (2) Industrial point sources are mostly distributed in the Yongding River system, presenting a banded distribution in the Yanghe River Basin. The high load of water pollutant of industrial point sources is near the river and the city, and high density areas of pollutant discharge are concentrated in Zhangbei county, Xuanhua district and Wanquan district. (3) The large, medium, small and micro enterprises are mainly concentrated in the Yongding River system under the dam, followed by the inland river system. Major emitters of heavily polluting industries are mainly located in Zhangbei, Guyuan and Kangbao county, and major emitters of light pollution industries are concentrated in the intersection of Zhongyang River and Qingshui River in the Yongding River system under the dam. By analyzing the spatial distribution pattern of industrial point sources and their pollution load characteristics, this study can provide guidance for government departments to adjust planning industries and focus on water polluted areas.