The measurement accuracy of the remote sensing satellite image points is of great significance for on-orbit geometric calibration of the satellite. To improve the measurement accuracy of ZY-3 satellite image points, four kinds of removable artificial signs with high and low reflectivity are designed. By the on-orbit test validation and a variety of measurement methods of the image points, the cross vertical angles sign is able to meet the design requirements of the minimum size and the best pattern is validated. The sign has good optical properties, physicochemical characteristics, and strong adaptability to the wild environment. The on-orbit test result indicates that this kinds of sign can be applied to the measurement of the current high-resolution, three-line array camera image points, and available to the predetermined 0.15 pixel measurement accuracy requirement of ZY-3 satellite on-orbit geometric calibration.