Satellite vibration was one of important factors which affected the performance of inter-satellite optical CDMA communication system. Considering the effects of multi-user interference,atmospheric scintillation,avalanche photodiode detector (APD) noise,thermal noise,and satellite vibration,the system model of intersatellite two-dimensional optical CDMA communication system with PPM signal format was presented,and the influence of satellite vibration on the bit error rate of this system was analyzed in detail.The results show that the wavelength,bit rate and satellite vibration could affect the bit error rate of intersatellite two-dimensional optical CDMA communication system all together. In the two-dimensional optical CDMA communication system which bit rate was 622 Mbps and wavelength was 1550 nm,when the standard variance was small (σ≤4 ×10^－7),it couldn't affect the bit error rate of this communication system severely. Otherwise,when the normal variance was large (σ≥l. 2×10^－6),the bit error rate couldn't satisfy the requirement of communication. Some methods needed to be used to suppress the influences of satellite vibration on the bit error rate of inter-satellite two-dimensional optical CDMA communication system.