Cement slurry powder contains components that can adsorb heavy metal ions, which can be used as adsorbent to treat wastewater containing heavy metal ions. In this experiment, ordinary Portland cement was used to prepare cement slurry powder with different hydration ages to treat wastewater containing Pb2+. The effects of age and dosage of cement slurry powder, Pb2+ concentration, pH value, temperature and adsorption time on Pb2+ removal effect and adsorption behavior were studied by means of X-ray diffraction, synchronous thermal analyzer and inductively coupled plasma. The test results show that the removal rate of lead ion in wastewater by cement slurry powder is generally greater than 80%. When 0.04 g cement slurry powder with water cement ratio of 0.50 and hydration age of 60 d is used for Pb2+ solution with initial concentration of 700 mg/L at 35 ℃, pH=2 and adsorption time of 200 min, the Pb2+ removal rate is 96.06% and the adsorption capacity is 336.22 mg/g. Through the study of adsorption thermodynamics and adsorption kinetics, it can be obtained that the adsorption thermodynamics of cement slurry powder for Pb2+ conforms to Freundlich adsorption isothermal model, and the adsorption kinetics conforms to pseudo first-order kinetic model.