Ground-based measurement is a principal method to obtain the infrared radiation characteristics of spatial target. The measuring result contains significant deviation caused by the atmosphere′s influence. The deviation can be reduced by using atmospheric synchronous correction system, which is composed of atmospheric optical parameters measurement equipment and radiation transfer software. However, due to the restriction of typical atmosphere models and precision of measured parameters, the corrected measurement accuracy is also greater than 20%. A radiation measurement method based on infrared standard star was proposed by using standard star which view pitch angle approximated to spatial target′s as a reference source, which could obtain precisely the transmittance of optical path from measurement system to spatial target, and the transmittance accuracy affected by water vapor, ozone and observation elevation were analyzed. The experiment of measuring the infrared stars was carried out. The radiation error of the target measured by this method is 4.65%, which is better than the classic method′s 14.57%. The result shows that the proposed method can provide an effective way for acquisition of infrared radiation characteristics of spatial target.