[1] E C Smyth, M Nilsson, H I Grabsch et al. Gastric cancer. Lancet, 396, 635-648(2020).
[2] J Machlowska, J Baj, M Sitarz et al. Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies. International Journal of Molecular Sciences, 21, 4012(2020).
[3] D A Sabbah, R Hajjo, K Sweidan. Review on epidermal growth factor receptor (EGFR) structure, signaling pathways, interactions, and recent updates of EGFR inhibitors. Current Topics in Medicinal Chemistry, 20, 815-834(2020).
[4] E Levantini, G Maroni, M Del Re et al. EGFR signaling pathway as therapeutic target in human cancers. Seminars in Cancer Biology, 85, 253-275(2022).
[5] A Saxena, D H Wu. Advances in therapeutic Fc engineering—modulation of IgG-associated effector functions and serum half-life. Frontiers in Immunology, 7, 580(2016).
[6] D Shi, Z Xu, Y Cheng et al. 124I-labeled immuno-PET targeting hTREM2 for the diagnosis of gastric carcinoma. Molecular Pharmaceutics, 20, 2235-2244(2023).
[7] Y Rathore, J Shukla, I Laroiya et al. Development 68Ga trastuzumab Fab and bioevaluation by PET imaging in HER2/neu expressing breast cancer patients. Nuclear Medicine Communications, 43, 458-467(2022).
[8] D Shi, S S Zhao, W Jiang et al. TLR5: a prognostic and monitoring indicator for triple-negative breast cancer. Cell Death & Disease, 10, 954(2019).
[9] Y Cheng, D Shi, Z Xu et al. 124I-labeled monoclonal antibody and fragment for the noninvasive evaluation of tumor PD-L1 expression in vivo. Molecular Pharmaceutics, 19, 3551-3562(2022).
[10] D Shi, Y Q Zhang, Z Xu et al. Noninvasive evaluation of EGFR expression of digestive tumors using 99mTc-MAG3-Cet-F(ab')2-based SPECT/CT imaging. Molecular Imaging, 2022, 3748315(2022).
[11] M A Kenna, R A Cooper, A D Schrieber. Effect of papain on the interaction between human monocytes, erythrocytes, and IgG. Blood, 46, 245-252(1975).
[12] C Leborgne, E Barbon, J M Alexander et al. IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies. Nature Medicine, 26, 1096-1101(2020).
[13] Y Z Wang, Q G Shi, H Lv et al. IgG-degrading enzyme of Streptococcus pyogenes (IdeS) prevents disease progression and facilitates improvement in a rabbit model of Guillain-Barré syndrome. Experimental Neurology, 291, 134-140(2017).
[14] C Armutcu, M E Çorman, E Bayram et al. Purification of Fab and Fc using papain immobilized cryogel bioreactor separator system. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 1158, 122396(2020).
[15] L Coleman, S M Mahler. Purification of Fab fragments from a monoclonal antibody papain digest by Gradiflow electrophoresis. Protein Expression and Purification, 32, 246-251(2003).
[16] D Shi, W H Fu, H Tan et al. Preclinical evaluation of 99mTc-MAG3-5-fab targeting TREM2 in lung cancer mouse models: a comparison with 99mTc-MAG3-5-F(ab')2. Molecular Pharmaceutics, 21, 303-312(2024).
