Yuan Jiangwei, Zhang Chunguang, Wang Hao, Shi Lei. Rapid Microscopic Spectral Imaging of Lung Cancer Tissue Based on Acousto-Optic Tunable Filter[J]. Chinese Journal of Lasers, 2018, 45(4): 407003
- Chinese Journal of Lasers
- Vol. 45, Issue 4, 407003 (2018)
Fig. 1. Vectorial diagram of noncollinear acoustic-optic interaction
Fig. 2. Experimental setup of the AOTF-based microscopic spectral imaging system
Fig. 3. Diffraction spectra of AOTF at the different acoustic frequencies. (a) 127 MHz; (b) 134 MHz; (c) 148 MHz; (d) 155 MHz; (e) 162 MHz; (f) 169 MHz
Fig. 4. Performance of AOTF-based microscopic spectral imaging system. (a) Relationship between spectral bandwidth of diffracted beam and central optical wavelength; (b) frequency tuning relation of noncollinear AOTF
Fig. 5. Hyperspectral images of lung cancer tissue with different center wavelengths of diffraction beams. (a) Without filtering; (b) 629.20 nm; (c) 576.21 nm; (d) 567.91 nm; (e) 542.12 nm; (f) 529.45 nm; (g) 503.84 nm; (h) 482.85 nm
Fig. 6. Relationship between the hyperspectral image intensity of the lung cancer tissue and the diffraction light center wavelength
Fig. 7. Intensity difference curves of target area and adjacent tissue
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Table 1. Main design parameters of AOTF
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Table 2. Parameters of diffraction light spectra under different ultrasonic frequencies
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