Thermal effect in crystals is the main obstacle blocking diode-pumped solid state laser to get high and stable output power. Diffusion bonding crystal has been demonstrated to be an effective method to relieve the thermal lensing theoretically based on the numerical heat analysis to the end-pumped anisotropic laser crystal. The temperature distributions in Nd:YVO4/YVO4 composite crystal and conventional crystal were analyzed and compared. The end-pumped Nd:YVO4/YVO4 composite crystal laser was designed and set up with z-cavity. The maximum output powers of 9.87 W at 1064 nm and 6.14 W at 532 nm were obtained at the incident pump power of 16.5 W. The highest optical-optical conversion efficiencies were up to 59.8% at 1064 nm and 37.2% at 532 nm respectively.