This paper presents the design of a highly stable semiconductor laser diode driver powered by FPGA. The driver is based on the Howland circuit principle, and the FPGA control method is adopted to realize the output current control of 0-500 mA and the current stability of 0.003% when the output current is 300 mA. When driving a 1 550 nm semiconductor laser with a butterfly package, the output optical power reaches 7.49 mW, and the optical power stability reaches 0.33%, which has an important significance for improving the stability of semiconductor laser output optical power.