• Journal of Innovative Optical Health Sciences
  • Vol. 14, Issue 1, 2140009 (2021)
Ziyi Zhang1, Tiepei Zhu2, Tongtong Cao1, Zhaoyu Gong1, Lin Yao1, Kaiyuan Liu1, Juan Ye2, and Peng Li1、3、*
Author Affiliations
  • 1State Key Lab of Modern Optical Instrumentation College of Optical Science and Engineering Zhejiang University, Hangzhou Zhejiang 310027, P. R. China
  • 2Eye center of the Second Affiliated Hospital College of Medicine, Zhejiang University Hangzhou, Zhejiang 310003, P. R. China
  • 3International Research Center for Advanced Photonics Zhejiang University, Hangzhou Zhejiang 310027, P. R. China
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    DOI: 10.1142/s1793545821400095 Cite this Article
    Ziyi Zhang, Tiepei Zhu, Tongtong Cao, Zhaoyu Gong, Lin Yao, Kaiyuan Liu, Juan Ye, Peng Li. Swept source intraoperative OCT angiography[J]. Journal of Innovative Optical Health Sciences, 2021, 14(1): 2140009 Copy Citation Text show less

    Abstract

    To accurately guide surgical instruments during ophthalmic procedures, some necessary intraoperative depth perception is required, which standard surgical microscopes supply limitedly. Intraoperative optical coherence tomography (iOCT), combining optical coherence tomography (OCT) technology and surgical microscope, enables noninvasive, real-time and highresolution cross-sectional imaging. Currently, though iOCT enables structural imaging, little research has been done on intraoperative angiography. In this work, we presented a swept-source intraoperative OCT angiography (SS-iOCTA) system based on a standard surgical microscope, which provides both structural and angiographic images. The feasibility of the proposed SSiOCTA was confirmed through deep anterior lamellar keratoplasty (DALK) of ex vivo porcine eyes and blood perfusion imaging of in vivo rat cortex. High-resolution intraoperative feedback, including sub-surface structure and angiogram of biological tissue, can be visualized simultaneously with the SS-iOCTA system, which expand the surgeon's capabilities and could be widely used in clinical surgery.
    Ziyi Zhang, Tiepei Zhu, Tongtong Cao, Zhaoyu Gong, Lin Yao, Kaiyuan Liu, Juan Ye, Peng Li. Swept source intraoperative OCT angiography[J]. Journal of Innovative Optical Health Sciences, 2021, 14(1): 2140009
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