A Bessel lens for laser cutting and beam measurement system are designed and developed. Additionally， picosecond Bessel beam is generated by a picosecond pulse laser and the designed Bessel lens， and it is used for the cutting experiment on a piece of silicate glass with the thickness of 1 mm. The results show that， by the incidence of a Gaussian beam with certain diameter on the Bessel lens， the central core diameter and non-diffracting propagation distance of the generated Bessel beam are 3.4 μm and 2.46 mm， respectively. In the cutting experiment， the diameters of the surface micro-holes before glass breaking are smaller than the designed central core diameter of Bessel beam. The designed Bessel lens and beam measurement system in this paper can satisfy the application requirements of laser cutting.