In order to realize molding process of polymer micro component (PMC) with high efficiency and high precision, the molding method of PMC is presented based on CO2 laser positioning irradiation. The software Comsol is used in the numerical analysis of the temperature of samples, two-dimensional (2D) and three-dimensional (3D) transient temperature field and distribution of samples are researched, and the influence of laser parameters on temperature variation is analyzed. The effects of processing parameters on replication quality are investigated via the development of test device and experiment. The results show that the appropriate laser parameters can meet the overall sample melting, and the higher the temperature, the better the molding precision; molding pressure is much lower than these of traditional injection molding and thermoforming. It is demonstrated that the proposed process is a feasible and effective way to laser melting-molding PMC.