Compared with other vortex beams, the perfect optical vortex (POV) beam has a more stable spatial intensity distribution because the beam radius is independent of the topological charge. In this paper, the transmission characteristics of the POV beam in slant path atmospheric turbulence are studied by means of multi-phase screen method and Fourier transform method. The influence of atmospheric turbulence on beam quality is analyzed by using beam drift and aperture average scintillation index. Then the beam quality of the POV beam and Gaussian vortex beam under the same transmission conditions is compared. The results show that POV beam has better beam stability than Gaussian vortex beam. When the topological load increases or the zenith angle decreases, the ability of POV beam to resist atmospheric turbulence increases. The resistance of POV beam to atmospheric turbulence can be improved by increasing the beam radius without changing the topological charge of the POV beam.