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Nano-Micro Letters
Vol. 16, Issue 1, 232 (2024)

Self-Healing Dynamic Hydrogel Microparticles with Structural Color for Wound Management

Li Wang^1,2,3, Xiaoya Ding⁴, Lu Fan^3,4, Anne M. Filppula³..., Qinyu Li^1,*, Hongbo Zhang^1,3,**, Yuanjin Zhao^1,2,*** and Luoran Shang^1,4,5,****|Show fewer author(s)

Author Affiliations

¹Department of General Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People’s Republic of China

²Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, People’s Republic of China

³Pharmaceutical Sciences Laboratory, Åbo Akademi University, 20520 Turku, Finland

⁴Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, People’s Republic of China

⁵Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, and the Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, People’s Republic of China

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DOI: 10.1007/s40820-024-01422-4 Cite this Article

Li Wang, Xiaoya Ding, Lu Fan, Anne M. Filppula, Qinyu Li, Hongbo Zhang, Yuanjin Zhao, Luoran Shang. Self-Healing Dynamic Hydrogel Microparticles with Structural Color for Wound Management[J]. Nano-Micro Letters, 2024, 16(1): 232 Copy Citation Text

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References

[1] S. Willenborg, S.A. Eming, Cellular networks in wound healing. Science 362, 891–892 (2018).

[2] V. Falanga, R.R. Isseroff, A.M. Soulika, M. Romanelli, D. Margolis et al., Chronic wounds. Nat. Rev. Dis. Primers. 8, 50 (2022).

[3] H. Chen, Y. Cheng, J. Tian, P. Yang, X. Zhang et al., Dissolved oxygen from microalgae-gel patch promotes chronic wound healing in diabetes. Sci. Adv. 6, eaba4311 (2020).

[4] Y. Liang, J. He, B. Guo, Functional hydrogels as wound dressing to enhance wound healing. ACS Nano 15, 12687–12722 (2021).

[5] M. Li, F. Fang, M. Sun, Y. Zhang, M. Hu et al., Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine. Theranostics 12, 4879–4903 (2022).

[6] Y. Feng, Z. Zhang, W. Tang, Y. Dai, Gel/hydrogel-based in situ biomaterial platforms for cancer postoperative treatment and recovery. Exploration 3, 20220173 (2023).

[7] S. Matoori, A. Veves, D.J. Mooney, Advanced bandages for diabetic wound healing. Sci. Transl. Med. 13, eabe4839 (2021).

[8] Y. Li, D. Hao, G. Feng, F.-J. Xu, A hydrogel wound dressing ideally designed for chronic wound care. Matter 6, 1060–1062 (2023).

[9] M. Kharaziha, A. Baidya, N. Annabi, Rational design of immunomodulatory hydrogels for chronic wound healing. Adv. Mater. 33, e2100176 (2021).

[10] J. Wang, X.-Y. Chen, Y. Zhao, Y. Yang, W. Wang et al., pH-switchable antimicrobial nanofiber networks of hydrogel eradicate biofilm and rescue stalled healing in chronic wounds. ACS Nano 13, 11686–11697 (2019).

[11] X. Du, B. Jia, W. Wang, C. Zhang, X. Liu et al., pH-switchable nanozyme cascade catalysis: a strategy for spatial-temporal modulation of pathological wound microenvironment to rescue stalled healing in diabetic ulcer. J. Nanobiotechnol. 20, 12 (2022).

[12] X. Ding, Y. Yu, C. Yang, D. Wu, Y. Zhao, Multifunctional GO hybrid hydrogel scaffolds for wound healing. Research 2022, 9850743 (2022).

[13] R. Yu, H. Zhang, B. Guo, Conductive biomaterials as bioactive wound dressing for wound healing and skin tissue engineering. Nano-Micro Lett. 14, 1 (2021).

[14] Q. Zeng, Q. Peng, F. Wang, G. Shi, H. Haick et al., Tailoring food biopolymers into biogels for regenerative wound healing and versatile skin bioelectronics. Nano-Micro Lett. 15, 153 (2023).

[15] L. Cai, D. Xu, H. Chen, L. Wang, Y. Zhao, Designing bioactive micro-/nanomotors for engineered regeneration. Eng. Regen. 2, 109–115 (2021).

[16] T. Cui, J. Yu, C.-F. Wang, S. Chen, Q. Li et al., Micro-gel ensembles for accelerated healing of chronic wound via pH regulation. Adv. Sci. 9, e2201254 (2022).

[17] J. Lan, L. Shi, W. Xiao, X. Zhang, S. Wang, A rapid self-pumping organohydrogel dressing with hydrophilic fractal microchannels to promote burn wound healing. Adv. Mater. 35, e2301765 (2023).

[18] Y.S. Zhang, C. Zhu, Y. Xia, Inverse opal scaffolds and their biomedical applications. Adv. Mater. 29, 1701115 (2017).

[19] B. Gao, M. Guo, K. Lyu, T. Chu, B. He, Intelligent silk fibroin based microneedle dressing (i-SMD). Adv. Funct. Mater. 31, 2006839 (2021).

[20] H. Wang, X. Chen, G. Xie, D. Bi, S. Du et al., Inverse opal photonic hydrogels for blue-edge slow photon-enhanced photodynamic antibacterial therapy. Adv. Funct. Mater. 33, 2306025 (2023).

[21] Y. Wang, X. Zhang, G. Chen, M. Lu, Y. Zhao, Multifunctional structural color triboelectric microneedle patches for psoriasis treatment. Matter 6, 1555–1568 (2023).

[22] L. Wang, G. Chen, L. Fan, H. Chen, Y. Zhao et al., Biomimetic enzyme cascade structural color hydrogel microparticles for diabetic wound healing management. Adv. Sci. 10, e2206900 (2023).

[23] M. Lu, X. Zhang, D. Xu, N. Li, Y. Zhao, Encoded structural color microneedle patches for multiple screening of wound small molecules. Adv. Mater. 35, e2211330 (2023).

[24] B.-D. Zheng, J. Ye, Y.-C. Yang, Y.-Y. Huang, M.-T. Xiao, Self-healing polysaccharide-based injectable hydrogels with antibacterial activity for wound healing. Carbohydr. Polym. 275, 118770 (2022).

[25] L. Cai, Y. Wang, L. Sun, J. Guo, Y. Zhao, Bio-inspired multi-responsive structural color hydrogel with constant volume and wide viewing angles. Adv. Opt. Mater. 9, 2100831 (2021).

[26] S. Kim, A.N. Mitropoulos, J.D. Spitzberg, H. Tao, D.L. Kaplan et al., Silk inverse opals. Nat. Photonics 6, 818 (2012).

[27] J.E.S.V. Hoeven, A.V. Shneidman, N.J. Nicolas, J. Aizenberg, Evaporation-induced self-assembly of metal oxide inverse opals: from synthesis to applications. Acc. Chem. Res. 55, 1809–1820 (2022).

[28] Y. Wang, L. Sun, G. Chen, H. Chen, Y. Zhao, Structural color ionic hydrogel patches for wound management. ACS Nano (2022).

[29] Y. Zhao, R. Li, B. Wang, Y. Huang, P. Lyu et al., Scalable structural coloration of carbon nanotube fibers via a facile silica photonic crystal self-assembly strategy. ACS Nano 17, 2893–2900 (2023).

[30] Z. Zhang, C. Wang, Q. Wang, Y. Zhao, L. Shang, Cholesteric cellulose liquid crystal ink for three-dimensional structural coloration. Proc. Natl. Acad. Sci. U.S.A. 119, e2204113119 (2022).

[31] L. Shang, Y. Yu, Y. Jiang, X. Liu, N. Sui et al., Ultrasound-augmented multienzyme-like nanozyme hydrogel spray for promoting diabetic wound healing. ACS Nano 17, 15962–15977 (2023).

[32] Z. Liu, W. Tang, J. Liu, Y. Han, Q. Yan et al., A novel sprayable thermosensitive hydrogel coupled with zinc modified metformin promotes the healing of skin wound. Bioact. Mater. 20, 610–626 (2022).

[33] P. Wang, L. Peng, J. Lin, Y. Li, Q. Luo et al., Enzyme hybrid virus-like hollow mesoporous CuO adhesive hydrogel spray through glucose-activated cascade reaction to efficiently promote diabetic wound healing. Chem. Eng. J. 415, 128901 (2021).

[34] L. Wang, L. Sun, F. Bian, Y. Wang, Y. Zhao, Self-bonded hydrogel inverse opal particles as sprayed flexible patch for wound healing. ACS Nano 16, 2640–2650 (2022).

[35] Z. Shao, T. Yin, J. Jiang, Y. He, T. Xiang et al., Wound microenvironment self-adaptive hydrogel with efficient angiogenesis for promoting diabetic wound healing. Bioact. Mater. 20, 561–573 (2022).

[36] Y. Liang, H. Xu, Z. Li, A. Zhangji, B. Guo, Bioinspired injectable self-healing hydrogel sealant with fault-tolerant and repeated thermo-responsive adhesion for sutureless post-wound-closure and wound healing. Nano-Micro Lett. 14, 185 (2022).

[37] X. Garrabou, B.I.M. Wicky, D. Hilvert, Fast Knoevenagel condensations catalyzed by an artificial Schiff-base-forming enzyme. J. Am. Chem. Soc. 138, 6972–6974 (2016).

[38] X. Ding, Y. Yu, W. Li, Y. Zhao, In situ 3D-bioprinting MoS2 accelerated gelling hydrogel scaffold for promoting chronic diabetic wound healing. Matter 6, 1000–1014 (2023).

[39] X. Ding, Y. Yu, L. Shang, Y. Zhao, Histidine-triggered GO hybrid hydrogels for microfluidic 3D printing. ACS Nano 16, 19533–19542 (2022).

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Li Wang, Xiaoya Ding, Lu Fan, Anne M. Filppula, Qinyu Li, Hongbo Zhang, Yuanjin Zhao, Luoran Shang. Self-Healing Dynamic Hydrogel Microparticles with Structural Color for Wound Management[J]. Nano-Micro Letters, 2024, 16(1): 232

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