When electromagnetic waves propagate through the atmosphere, the turbulence causes phase fluctuations and degrades the image quality of the photoelectric system. Adaptive optics is used to correct the effect of atmospheric turbulence, but in order to optimize system performance, as well as the large telescope sitting, designing and operating, monitoring optical turbulence intensity and integral parameters of the observing stations are necessary. Measuring atmospheric optical turbulence takes a huge labor, materials and financial resources, and it is difficult to measure a large region continuously. The weather research and forecasting (WRF) model is introduced based on the optical turbulence parameterization, the profiles of the optical turbulence intensity are simulated using turbulence parameterized model. Simulation results are compared with measurements at Gaomeigu observing station, the results show that the simulation profiles emerge the variation tendency of the upper air atmospheric optical turbulence, and basically coincide with the measurements.