Based on atmospheric infrared sounder (AIRS ) satellite data from December 2002 to November 2016, the spatial-temporal characteristics of CO2 concentration in different seasons over globe and East Asia (70～140°E, 10～55°N) were analyzed and compared with the surface observation data. The results show that: 1) the correlation coefficient between the CO2 data of AIRS and the surface observation data is above 0.9, and the relative error of annual mean value is within 1%. 2) The global annual mean CO2 concentration increased from 357.16 ml/m3 in 2003 to 401.24 ml/m3 in 2016, with an average annual growth date of about 2.01 ml/m3. While it increased from 357.13 ml/m3 to 402.22 ml/m3 during the same period over East Asia, with an average annual growth rate of about 2.08 ml/m3 which is a bit higher than that of globe. Over most of the Northern Hemisphere, the CO2 concentration growth rate during 2010～2016 is lower than that of during 2003～2009. In particular, mean CO2 concentration increased markedly over central Siberia and Greenland. 3) The distributions of CO2 concentrations had obviously regional features. The regions with high CO2 concentration were over middle and high latitudes in the Northern Hemisphere, whereas the regions wtih low CO2 concentration were mainly located over Tibet Plateau. In the Southern Hemisphere, the regions with high concentration was located in the middle latitudes, while the region with low concentration was located in the low latitudes of Atlantic (0～20°S, 50°W～5°E). In the middle and lower troposphere (4～6 km), the seasonal variation characteristics of CO2 concentration retrieved by AIRS was highly reliable. Especially in winter, over most of the Northern Hemisphere, CO2 concentration decreased first and then increased with time. 4) In East Asia, the high CO2 concentration was located in the Northern China with zonal distribution.