Females are important force in promoting social development. As the most direct way for women to participate in social and economic developments, employment has always been an important topic in scientific research. Taking the old industrial bases in Northeast China as an example, this study explored the spatial and temporal characteristics and driving mechanism of urban female employment level by means of spatial analysis. The results show that: 1) The level of urban female employment in the old industrial bases in Northeast China from 2000 to 2015 was generally low, mainly at medium and low levels; the medium level was mainly found in the central and southern regions, and the lower level was mainly distributed in the north. 2) From the analysis of influencing factors, it can be seen that higher education, convenient transportation, developed industries, the proportion of women with spouses, the proportion of the elderly aged 65 and above, and the proportion of households with three or more generations had a positive effect on the level of urban female employment, while demographic pressure had a negative effect on female employment level. Obviously, a complete family plays an extremely important role in female employment. 3) The government should integrate all sectors of society, encourage social capital to participate in the development of the elderly and childcare, and provide more and better quality services to families with strong needs for elderly care and childcare. In addition, promote the "family" culture of "respecting the old, loving the young, and being friendly with neighbors", encourage family members to participate in housework together, build an equal relationship between men and women in housework, create a harmonious family environment and social atmosphere, and relieve women conflict between work and housework.