Fluorescence microendoscopy imaging based on GRIN lenses with one- and two-photon excitation modes

Wei YAN; Xiao PENG; Danying LIN; Qi WANG; Jian GAO; Teng LUO; Jie ZHOU; Tong YE; Junle QU; Hanben NIU

doi:10.1007/s12200-015-0503-1

[1] Lakowicz J R. Principles of Fluorescence Spectroscopy. 3rd ed. New York: Springer, 2006

[2] Denk W, Strickler J H, Webb W W. Two-photon laser scanning fluorescence microscopy. Science, 1990, 248(4951): 73–76

[3] Peter T C S. Two-photon fluorescence light microscopy. Encyclopedia of Life Science, 2002, Macmillan Publishers Ltd, Nature Publishing Group. www.els.net

[4] Jung J C, Schnitzer M J. In vivo epi-fluorescence micor-endoscopy. Biophysical Journal, 2002, 82: 496a–497a

[5] Levene M J, Dombeck D A, Kasischke K A, Molloy R P, Webb W W. In vivo multiphoton microscopy of deep brain tissue. Journal of Neurophysiology, 2002, 91: 1908–1912

[6] Elangovan M,Wallrabe H, Chen Y, Day R N, Barroso M, Periasamy A. Characterization of one- and two-photon excitation fluorescence resonance energy transfer microscopy. Methods (San Diego, Calif.), 2003, 29(1): 58–73

[7] Jung J C, Mehta A D, Aksay E, Stepnoski R, Schnitzer M J. In vivo mammalian brain imaging using one- and two-photon fluorescence micorendoscopy. Journal of Neurophysiology, 2004, 92: 3121–3133

[8] Campagnola P J, Loew LM. Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms. Nature Biotechnology, 2003, 21(11): 1356–1360

[9] Qu J, Liu L, Shao Y, Niu H, Gao B Z. Recent progress in multifocal multiphoton microscopy. Journal of Innovative Optical Health Science, 2012, 05(03): 1250018

[10] Pillai R S, Lorenser D, Sampson D D. Deep-tissue access with confocal fluorescence microendoscopy through hypodermic needles. Optics Express, 2011, 19(8): 7213–7221

[11] Li X, Yu W. Deep tissue microscopic imaging of the kidney with a gradient-index lens system. Optics Communications, 2008, 281(7): 1833–1840

[12] Saunter C D, Semprini S, Buckley C, Mullins J, Girkin J M. Microendoscope for in vivo widefield high spatial resolution fluorescent imaging. Biomedical Optics Express, 2012, 3(6): 1274–1278

[13] Kim P, Puoris’haag M, C té D, Lin C P, Yun S H. In vivo confocal and multiphoton microendoscopy. Journal of Biomedical Optics, 2008, 13(1): 010501

[14] Huland D M, Brown C M, Howard S S, Ouzounov D G, Pavlova I, Wang K, Rivera D R, Webb W W, Xu C. In vivo imaging of unstained tissues using long gradient index lens multiphoton endoscopic systems. Journal of biomedical optics, 2012, 3(5): 1077–1085

[15] Yang C, Hou V, Nelson L Y, Seibel E J. Mitigating fluorescence spectral overlap in wide-field endoscopic imaging. Journal of Biomedical Optics, 2013, 18(8): 086012

[16] Kyrish M, Utzinger U, Descour M R, Baggett B K, Tkaczyk T S. Ultra-slim plastic endomicroscope objective for non-linear microscopy. Optics Express, 2011, 19(8): 7603–7615

[17] Wang C, Ji N. Characterization and improvement of three dimensional imaging performance of GRIN-lens-based two-photon fluorescence endomicroscopes with adaptive optics. Optics Express, 2013, 21(22): 27142–27154

[18] Qi J, Shao Y, Liu L, Wang K, Chen T, Qu J, Niu H. Fast flexible multiphoton fluorescence lifetime imaging using acousto-optic deflector. Optics Letters, 2013, 38(10): 1697–1699

[19] Krasieva T B, Stringari C, Liu F, Sun C H, Kong Y, Balu M, Meyskens F L, Gratton E, Tromberg B J. Two-photon excited fluorescence lifetime imaging and spectroscopy of melanins in vitro and in vivo. Journal of Biomedical Optics, 2013, 18(3): 031107

[20] Yan W, Peng X, Qi J, Gao J, Fan S, Wang Q, Qu J, Niu H. Dynamic fluorescence lifetime imaging based on acousto-optic deflectors. Journal of Biomedical Optics, 2014, 19(11): 116004