This paper analyzes the problems existing in the engineering training and innovation practice platform of universities and their adverse effects on the cultivation of innovative talents. It puts forward the construction measures of the open engineering training and innovation practice platform and the open management mode of public resources. Furthermore, it has formed a multi-dimensional innovative practice and talent training system, which has combined practice and training, independent innovation, discipline competition and school enterprise cooperation as a whole. The system is suitable for students’ autonomous learning and conducive to students’ personality development, which has advanced concept and scientific structure. It has a certain reference significance for the construction of engineering training center of comprehensive university.