The irradiation parameters are the foundation to study damage effect of flying target by laser, which include the location of irradiation center point, irradiation area and power density distribution. Taking the laser irradiating horizontal uniform moving target and parabolic moving target as the background respectively, the assumed encounter scene and parameters are given. Then, the analytical calculation models of the location of irradiation center point, irradiation area and power density distribution are derived. The simulation results show that the irradiation parameters vary with the rolling and flying of target. The power density distribution in irradiation area is a varying three-dimensional elliptic Gaussian function. The rolling of target results in varying of location of irradiation center point and irradiation area, and influences temperature field of target and damage effect by laser. The analytical solutions are foundations for analyzing the effect of laser irradiating flying target.