To obtain gradient coating with changed components and properties, the gradient coating comprised of two-kind metal powders (Ni25/Ni60 and AlSi12/Fe62) is fabricated with paraxonic synchronism powder feeding mode, 2.5 kW high power diode laser and 4 channels powder system. The 9-mm width spiral gradient coatings on 45# steel stick are achieved. Meanwhile, energy dispersive spectroscopy (EDS), microstructure and micro-hardness of coating are studied. The experimental results show that along the forming direction, the content of element Cr and the micro-hardness decrease continuously in Ni25/Ni60 gradient coating; the contents of elements Fe, Cr and Al change continuously in AlSi12/Fe62 gradient coating; the microstructures in both coatings change obviously.