Laser-driven flyer micro-punching technology is a micro-holes manufacturing process. When an intense laser pulse irradiates onto the ablative layer, a flyer with high speed will impact the thin metal workpiece thus punching is completed. In this experiment, a short pulse Nd-YAG laser (INNOLAS Spitlight 2000) is employed, and Al foils with thickness of 20 μm are employed as flayers. AISI 1095 high-carbon steel is used as material of die, whose hardness is 58 HRC. The sheet used to make punching die is 0.5 mm in thickness and the through die-openings array in the center position are fabricated by picosecond laser. Three plum-like micro holes with 500 μm in diameter are punched simultaneously on the 20 μm thick Al foils. Under the KEYENCE VHX-1000C digital microscope, it can be found that the quality of sheared edges is good, there is an appropriate rollover zone between upper surface and punched fracture, burrs are also reduced a lot. In addition, simulations are conducted by ANSYS/LS-DYNA. The methods of finite element mesh (FEM) and smoothed particle hydrodynamics (SPH) are used. In the simulation, formation process of fracture, equivalent stress distribution, equivalent plastic strain distribution and evolution of displacement of specified particles are studied to analyze basic characteristics of laser-driven flyer micro-punching technology.