The rapid development of infrared imaging devices and infrared imaging guidance technology has led to the rapid development of infrared imaging guided weapons. Infrared imaging guided anti-ship missiles have become one of the main combat weapons of national navies. Infrared imaging guided anti-ship missiles pose a great threat to naval vessels. Starting from the principle of missile guidance and attack mode, the performance, characteristics and countermeasures of countermeasure equipment are studied. By analyzing the working mode of the missile and the basic principle of the photoelectric countermeasure equipment, the implementation scheme of the anti-ship missile against infrared imaging guidance is preliminarily discussed, which provides technical support for infrared imaging guided weapons and the ship against infrared imaging guided missiles.