In order to realize the image stabilization and provide theory basis for the damping device design of camera platform, the impact of los jitter on image quality is analyzed. The reason how the los jitter produces and the characteristics of los jitter are analyzed. Based on the analysis, a new algorithm of the analysis of vibration blurred images based on the image gray-scale is proposed. The simulation results of blurred image caused by los jitter are obtained according to the simulation model. A set of vibration imaging device is built to verify the simulation results, and the device can get a blurred image by loading a vibration. Using mean square error (MSE) to measure image quality, the results show that in the range of permitted errors, the results of the impact of los jitter on image quality between simulation and experiment remain the same, which indicates the correctness of the simulation analysis. In practical applications, this method can effectively simulate the impact of los jitter on image quality.