High accuracy of target aiming and positioning is required in the study of the inertial confinement fusion (ICF). A system based on the chamber center reference system, the target positing system and the target alignment sensor is designed. The finite element method is used for analyzing the static deformation and transient stability of this system, and it proposes a calibration method of the high resolution parallel light pipe to achieve the system coupling precision. It achieves target aiming and positioning precision better than 12 μm of the SG-II updated laser facility. Through the SG-II updated laser facility single laser beam across the Φ 800 μm hole target, the perforation efficiency is 97.5%. This provides a solid foundation for high accuracy targeting of the follow-up physical experiment′s requirement.