Fig. 1. Application research of fluorescent carbon quantum dots in biomedical field

Fig. 2. Application of carbon dots in field of bioimaging. (a) Confocal fluorescence images of six carbon dots targeting different parts of A549 cells^[17]; (b) carbon point synthesis roadmap and its imaging in vivo and in living cells in zebrafish^[18]; (c) dual-mode imaging diagram of carbon dots used for fluorescence imaging and nuclear magnetic imaging of cerebellar glioma^[20]; (d) carbon point is used for in vivo imaging of silkworm^[21]

Fig. 3. Application of carbon point in field of disease diagnosis. (a) Carbon point monitoring of environmental pH changes in zebrafish and living cells^[25]; (b) map of glycolysis mechanism of carbon point sensing in vivo^[26]; (c) preparation of carbon points and sensing mechanism of cytochrome C^[31]; (d) prepared proportional fluorescent carbon points are used for fluorescence sensing and visual detection of ATP and creatine kinase (CK) ^[32]

Fig. 4. Application of carbon point in direction of disease treatment. (a) Schematic of carbon dots penetrating blood-brain barrier and targeting mitochondria for tumor therapy^[42]; (b) preparation process of carbon point and schematic of phototherapy and chemotherapy synergistic treatment of mouse tumor^[43]; (c) synthesis of quaternary ammoniated carbon points and schematic of antibacterial mechanism^[45]; (d) preparation of carbon points of levofloxacin and schematic of antibacterial therapy in mice^[50]; (e) schematic of broccoli source carbon point clearing ROS for treatment of inflammation in cells and zebrafish^[48]; (f) schematic of cardamine carbon points accelerate wound repair by removing ROS and anti-inflammatory ^[49]

Table 1. Summary of application of carbon points in biomedical field in recent years