Rectal and bladder dose prediction in volumetric modulated arc therapy for cervical cancer based on dose-volume histogram

Ping ZHENG; Dong WANG

doi:10.11889/j.1000-3436.2022-0039

Journals >Journal of Radiation Research and Radiation Processing >Volume 40 >Issue 5 >Page 050303 > Article

Journal of Radiation Research and Radiation Processing
Vol. 40, Issue 5, 050303 (2022)

Rectal and bladder dose prediction in volumetric modulated arc therapy for cervical cancer based on dose-volume histogram

Ping ZHENG and Dong WANG^*

Author Affiliations

Room of Radiotherapy, Zigong First People's Hospital, Zigong 643000, China

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DOI: 10.11889/j.1000-3436.2022-0039 Cite this Article

Ping ZHENG, Dong WANG. Rectal and bladder dose prediction in volumetric modulated arc therapy for cervical cancer based on dose-volume histogram[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(5): 050303 Copy Citation Text

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Relationship between the intersection volume and the expansion distance: (a) 3D visualization; (b) the cross-sectional schematic diagram (the rectum for an example, as is similar to bladder) (color online)

Fig. 1. Relationship between the intersection volume and the expansion distance: (a) 3D visualization; (b) the cross-sectional schematic diagram (the rectum for an example, as is similar to bladder) (color online)

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Fig. 2. Contribution rates of feature vector

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Fig. 3. Comparison of predicted and actual values: (a) bladder V₄₀; (b) bladder D₃₃; (c) rectum V₄₀; (d) rectum D₃₃

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Fig. 4. Prediction relative error of validation set (color online)

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危及器官 Organs at risk	剂量体积限值 Dose volume limit
膀胱Bladder	V₄₀<60%	D₃₃<45Gy
直肠Rectum	V₄₀<60%	D₃₃<45Gy
左股骨头Femoral head_left	V₄₅<5%	V₃₀<30%
右股骨头Femoral head_right	V₄₅<5%	V₃₀<30%
小肠Small bowel	V₃₀<30%
脊髓Spinal cord	D_max<45 Gy

Table 1. Dose limit of organs at risks

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系数 Coefficient	膀胱 Bladder V₄₀	膀胱 Bladder D₃₃	直肠 Rectum V₄₀	直肠 Rectum D₃₃
C₀	3.60	3 362.40	25.96	3 401.62
C₁	-30.10	-682.54	-10.64	-389.58
C₂	0.66	-3.09	0.12	12.27
C₃	0.66	10.36	0.60	8.57
C₄	-22.15	-666.55	-0.68	-216.20
C₅	0.00	-21.54	0.24	0.51
C₆	-0.20	-1.36	-0.16	-2.54
C₇	-133.99	-3 560.82	-46.59	-2 332.70
C₈	4.74	-6.27	-2.08	-133.89
C₉	10.48	225.24	3.96	123.89
C₁₀	190.09	5 346.39	59.62	3 215.10
C₁₁	-0.99	72.56	2.07	244.57
C₁₂	-13.48	-409.14	-3.73	-230.82
C₁₃	9.67	113.14	12.82	460.62
C₁₄	6.22	154.24	1.87	192.86
C₁₅	-13.50	-266.78	-7.52	-279.44
C₁₆	-54.99	-1 571.39	-16.95	-1 068.73
C₁₇	-0.18	169.40	2.86	378.12
C₁₈	-5.05	-70.14	-3.67	112.73
C₁₉	-2.90	-39.86	-2.74	-703.22
C₂₀	11.37	-113.32	6.63	-138.03
C₂₁	-4.12	-203.70	-7.59	217.48

Table 2. Multivariate nonlinear regression model coefficients for predicting bladder and rectum dose

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