The application of coal mining gas multipoint monitoring with tunable diode laser absorption spectroscopy(TDLAS) technique is studied. The principle and design scheme of real-time monitoring of multipoint gas concentration system which based on spectroscopy absorption principle is analyzed. The TDLAS technique, distributed fiber sensing technique and time division multiplexing detection technique are integrated to achieve optical sensing of multipoint gas concentration. Considering the requirement of real-time measurement, a new inversion method by insetting a calibration cell with standard concentration gas into the optical path is introduced. The system's performance is tested by measuring gas of different concentrations. The detection limit is below 60×10^－6. It proves that the scheme is feasible, and the technology has characteristics of real-time, successive, non-intrusive and fast measurement, so it can meet the requirements of coal mining gas monitoring.