In this paper, the effects of different pretreatment methods and high performance coating cementitious materials on physical properties, chloride ion dissolution behavior and mechanical properties of reef aggregate were studied. The reef aggregate pretreated by coating was used to prepare reef concrete, and the effects of pretreatment method and aggregate replacement level on the mechanical properties, chloride ion permeability and volume stability of reef concrete were discussed. The results show that the pretreatment method of standby after evenly coated the aggregate with slurry and then drying in oven exhibits the best aggregate modification results than other pretreatment methods, and the technical properties of reef aggregate such as void fraction, water absorption, crushing value and chloride ion dissolution characteristics are optimized. When the reef aggregate is added into concrete with the volume replacement of 20%, 40% and 60%, comparing with uncoated reef concrete, the compressive strength of coated reef concrete increases by 6.67%, 15.40% and 20.05% at 28 d, the diffusion coefficient of chloride ion decreases by 6.25%, 17.31% and 38.10%, and the drying shrinkage reduces by 5.81%, 17.05% and 24.43%, respectively. After coating, the interface transition zone between reef aggregate and cement mortar is modified, and the mechanical properties, chloride ion permeability and volume stability of reef concrete are improved.