With the home-made laser rapid forming system and suitable processing parameter, functionally graded materials (FGMs) were prepared whose compositions continuously gradually changed from 100% 316L to 100% Rene 88 DT. The microstructure of prepared materials was full dense and very fine, its composition and hardness were continuously varied in the 40-mm transition layers. In the transition layers, with Rene 88DT′s percentage composition increased, the degree of hardness and primary dendritic space were varied from 186 Hv, 12.41 μm with 100% 316L at the bottom to 458 Hv, 16.99 μm with 100% Rene 88DT in the top.