Surface-enhanced Raman effect of new coronavirus S protein in gold nanoparticles

Wei Le; Jinglin Huang; Qiang Yang; Daojian Qi; Shuang Ni; Lai Wei; Quanping Fan; Yue Yang; Jiaxing Wen; Wenbo Mo; Guo Chen; Songnan Zhao; Zhibing He; Bo Li; Kai Du

doi:10.11884/HPLPB202133.210466

Journals >High Power Laser and Particle Beams >Volume 33 >Issue 11 >Page 119001 > Article

High Power Laser and Particle Beams
Vol. 33, Issue 11, 119001 (2021)

Surface-enhanced Raman effect of new coronavirus S protein in gold nanoparticles

Wei Le¹, Jinglin Huang¹, Qiang Yang², Daojian Qi¹, Shuang Ni¹, Lai Wei^1、3, Quanping Fan^1、3, Yue Yang^1、3, Jiaxing Wen³, Wenbo Mo³, Guo Chen¹, Songnan Zhao¹, Zhibing He¹, Bo Li¹, and Kai Du^1、*

Author Affiliations

¹Laser Fusion Research Center, CAEP, Mianyang 621900, China

²China Academy of Engineering Physics, Mianyang 621900, China

³Science and Technology on Plasma Physics Laboratory, Mianyang 621900, China

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DOI: 10.11884/HPLPB202133.210466 Cite this Article

Wei Le, Jinglin Huang, Qiang Yang, Daojian Qi, Shuang Ni, Lai Wei, Quanping Fan, Yue Yang, Jiaxing Wen, Wenbo Mo, Guo Chen, Songnan Zhao, Zhibing He, Bo Li, Kai Du. Surface-enhanced Raman effect of new coronavirus S protein in gold nanoparticles[J]. High Power Laser and Particle Beams, 2021, 33(11): 119001 Copy Citation Text

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Fig. 1. Raman spectrum of the S protein of SARS-CoV-2 in solid state

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Fig. 2. Raman spectrum of the S protein of SARS-CoV-2 in saturated liquid state

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Fig. 3. Conventional Raman spectrum and SERS spectra of the S protein of SARS-CoV-2

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peak of pure solid SARS-CoV-2/cm⁻¹	peak of SARS-CoV-2 in saturated liquid state/cm⁻¹	SERS of SARS-CoV-2/cm⁻¹	assignment of the bands
537.7	524.7	523.3	S−S stretching vibration
679.1	/	742.6	COO⁻ rocking vibration
851.6	850.7	836.2	NH₂ rocking vibration
915.3	917.1	927.6	C−C symmetrical expansion
1111.1	1111.4	1126.3	C−N rocking vibration
1250.9	/	1211.5	CH₂ symmetrical deformation
1326.4	1257.2	1263.5	COO⁻ symmetrical stretching vibration
1362.7	1343.6	1357.3	tryptophan

Table 1. Raman peaks (cm⁻¹) and their assignment of the S protein of SARS-CoV-2^[14−16]

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